Nicotine, Vaping & Anxiety: Key Insights Clutch Vape Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental Vaping and Anxiety: Why They're Connected Vaping isn't helping reduce your stress, anxiety or depression. Here's what's actually happening in your brain. Nicotine gives you a quick dopamine hit that lasts maybe 5 minutes. Then it crashes. You If you vape to cope with stress or anxiety, you might be making it worse. Nicotine, a chemical commonly found in vapes and e cigarettes, is addictive and can cause a cycle of dependence. Our The New Mental Fog: How the Vaping Epidemic Impacts the Teen Mental Health Crisis Tobacco Stops With Me